Top Public Companies by Net Loss
Public companies with the largest reported net losses from their most recent 10-K filing.
Rankings are based on the most recent full fiscal year (FY) value reported in each company's 10-K annual filing with the SEC. Only companies with XBRL-tagged financial data are included. All figures are as reported — negative values indicate a loss. Use the metric tabs to compare across revenue, net income, assets, and more.
Revenue
Net Income
Net Loss
Total Assets
Cash & Equivalents
Long-Term Debt
Profit Margin
Return on Assets
| # | Company | Industry | Net Loss | FY |
|---|---|---|---|---|
| 401 |
Seritage Growth Properties
SRG-PA
NYSE
|
Real Estate | ($154.91M) | FY2023 |
| 402 |
Mineralys Therapeutics, Inc.
MLYS
NASDAQ
|
Pharmaceutical Preparations | ($154.65M) | FY2025 |
| 403 |
CRESCENT BIOPHARMA, INC.
CBIO
NASDAQ
|
Pharmaceutical Preparations | ($153.94M) | FY2025 |
| 404 |
UroGen Pharma Ltd.
URGN
NASDAQ
|
Pharmaceutical Preparations | ($153.49M) | FY2025 |
| 405 |
Core Natural Resources, Inc.
CNR
NYSE
|
Silver Ores | ($153.22M) | FY2025 |
| 406 |
American Bitcoin Corp.
ABTC
NASDAQ
|
Finance Services | ($153.17M) | FY2025 |
| 407 |
MASIMO CORP
MASI
NASDAQ
|
Electromedical & Electrotherap... | ($151.50M) | FY2025 |
| 408 |
HORIZON BANCORP INC /IN/
HBNC
NASDAQ
|
State Commercial Banks | ($150.48M) | FY2025 |
| 409 |
W&T OFFSHORE INC
WTI
NYSE
|
Crude Petroleum & Natural Gas | ($150.06M) | FY2025 |
| 410 |
Empery Digital Inc.
EMPD
NASDAQ
|
Motor Vehicles & Passenger Car... | ($150.05M) | FY2025 |
| 411 |
PLIANT THERAPEUTICS, INC.
PLRX
NASDAQ
|
Pharmaceutical Preparations | ($149.34M) | FY2025 |
| 412 |
Applied Digital Corp.
APLD
NASDAQ
|
Services-Computer Processing &... | ($149.27M) | FY2024 |
| 413 |
Atai Beckley N.V.
ATAI
NASDAQ
|
Pharmaceutical Preparations | ($149.27M) | FY2024 |
| 414 |
TON Strategy Co
TONX
NASDAQ
|
Services-Personal Services | ($148.48M) | FY2025 |
| 415 |
Caribou Biosciences, Inc.
CRBU
NASDAQ
|
Biological Products, (No Diagn... | ($148.13M) | FY2025 |
| 416 |
P3 Health Partners Inc.
PIIIW
NASDAQ
|
Services-Health Services | ($147.95M) | FY2024 |
| 417 |
ALICO, INC.
ALCO
NASDAQ
|
Agricultural Production-Crops | ($147.33M) | FY2025 |
| 418 |
DBV Technologies S.A.
DBVTF
OTC
|
Biological Products, (No Diagn... | ($146.95M) | FY2025 |
| 419 |
URBAN ONE, INC.
UONEK
NASDAQ
|
Radio Broadcasting Stations | ($146.87M) | FY2025 |
| 420 |
ASPEN INSURANCE HOLDINGS LTD
AHL-PF
NYSE
|
Fire, Marine & Casualty Insura... | ($146.80M) | FY2018 |
| 421 |
AbCellera Biologics Inc.
ABCL
NASDAQ
|
Pharmaceutical Preparations | ($146.41M) | FY2025 |
| 422 |
Aeva Technologies, Inc.
AEVA
NASDAQ
|
Motor Vehicle Parts & Accessor... | ($145.43M) | FY2025 |
| 423 |
Net Lease Office Properties
NLOP
NYSE
|
Real Estate Investment Trusts | ($145.26M) | FY2025 |
| 424 |
Amylyx Pharmaceuticals, Inc.
AMLX
NASDAQ
|
Pharmaceutical Preparations | ($144.74M) | FY2025 |
| 425 |
CHARLES RIVER LABORATORIES INTERNATIONAL, INC.
CRL
NYSE
|
Services-Commercial Physical &... | ($144.34M) | FY2025 |
| 426 |
Entrada Therapeutics, Inc.
TRDA
NASDAQ
|
Pharmaceutical Preparations | ($143.75M) | FY2025 |
| 427 |
Upstream Bio, Inc.
UPB
NASDAQ
|
Pharmaceutical Preparations | ($143.44M) | FY2025 |
| 428 |
Alphatec Holdings, Inc.
ATEC
NASDAQ
|
Surgical & Medical Instruments... | ($143.36M) | FY2025 |
| 429 |
indie Semiconductor, Inc.
INDI
NASDAQ
|
Semiconductors & Related Devic... | ($143.07M) | FY2025 |
| 430 |
Alector, Inc.
ALEC
NASDAQ
|
Biological Products, (No Diagn... | ($142.93M) | FY2025 |
| 431 |
ADC Therapeutics SA
ADCT
NYSE
|
Pharmaceutical Preparations | ($142.62M) | FY2025 |
| 432 |
Structure Therapeutics Inc.
GPCR
NASDAQ
|
Pharmaceutical Preparations | ($141.20M) | FY2025 |
| 433 |
FRACTYL HEALTH, INC.
GUTS
NASDAQ
|
Surgical & Medical Instruments... | ($140.95M) | FY2025 |
| 434 |
4D Molecular Therapeutics, Inc.
FDMT
NASDAQ
|
Biological Products, (No Diagn... | ($140.11M) | FY2025 |
| 435 |
Inhibrx Biosciences, Inc.
INBX
NASDAQ
|
Biological Products, (No Diagn... | ($140.06M) | FY2025 |
| 436 |
Skillsoft Corp.
SKILW
OTC
|
Services-Prepackaged Software | ($139.82M) | FY2026 |
| 437 |
Orion Properties Inc.
ONL
NYSE
|
Real Estate Investment Trusts | ($139.31M) | FY2025 |
| 438 |
JBG SMITH Properties
JBGS
NYSE
|
Real Estate Investment Trusts | ($139.06M) | FY2025 |
| 439 |
Definitive Healthcare Corp.
DH
NASDAQ
|
Services-Prepackaged Software | ($138.93M) | FY2025 |
| 440 |
EAGLE BANCORP INC
EGBN
NASDAQ
|
State Commercial Banks | ($138.05M) | FY2025 |
| 441 |
Bicara Therapeutics Inc.
BCAX
NASDAQ
|
Pharmaceutical Preparations | ($137.95M) | FY2025 |
| 442 |
IP STRATEGY HOLDINGS, INC.
IPST
NASDAQ
|
Beverages | ($137.72M) | FY2025 |
| 443 |
BRUNSWICK CORP
BC-PC
NYSE
|
Engines & Turbines | ($137.30M) | FY2025 |
| 444 |
Zentalis Pharmaceuticals, Inc.
ZNTL
NASDAQ
|
Pharmaceutical Preparations | ($137.06M) | FY2025 |
| 445 |
Frontier Group Holdings, Inc.
ULCC
NASDAQ
|
Air Transportation, Scheduled | ($137.00M) | FY2025 |
| 446 |
MAXLINEAR, INC
MXL
NASDAQ
|
Semiconductors & Related Devic... | ($136.68M) | FY2025 |
| 447 |
FATE THERAPEUTICS INC
FATE
NASDAQ
|
Biological Products, (No Diagn... | ($136.32M) | FY2025 |
| 448 |
NovoCure Ltd
NVCR
NASDAQ
|
Surgical & Medical Instruments... | ($136.23M) | FY2025 |
| 449 |
OFFICE PROPERTIES INCOME TRUST
OPITQ
|
Real Estate | ($136.11M) | FY2024 |
| 450 |
GPGI, Inc.
GPGI
NYSE
|
Finance Services | ($136.01M) | FY2025 |
| 451 |
Sweetgreen, Inc.
SG
NYSE
|
Retail-Eating Places | ($134.07M) | FY2025 |
| 452 |
BridgeBio Oncology Therapeutics, Inc.
BBOT
NASDAQ
|
Pharmaceutical Preparations | ($134.04M) | FY2025 |
| 453 |
Ondas Inc.
ONDS
NASDAQ
|
Radio & Tv Broadcasting & Comm... | ($132.24M) | FY2025 |
| 454 |
Sleep Number Corp
SNBR
NASDAQ
|
Household Furniture | ($131.96M) | FY2025 |
| 455 |
Braze, Inc.
BRZE
NASDAQ
|
Services-Prepackaged Software | ($131.29M) | FY2026 |
| 456 |
Maze Therapeutics, Inc.
MAZE
NASDAQ
|
Biological Products, (No Diagn... | ($131.12M) | FY2025 |
| 457 |
Outdoor Holding Co
POWWP
NASDAQ
|
Ordnance & Accessories, (No Ve... | ($130.83M) | FY2025 |
| 458 |
MARAVAI LIFESCIENCES HOLDINGS, INC.
MRVI
NASDAQ
|
Pharmaceutical Preparations | ($130.77M) | FY2025 |
| 459 |
Cartesian Therapeutics, Inc.
RNAC
NASDAQ
|
Pharmaceutical Preparations | ($130.30M) | FY2025 |
| 460 |
NEXPOINT DIVERSIFIED REAL ESTATE TRUST
NXDT-PA
NYSE
|
Real Estate Investment Trusts | ($130.19M) | FY2025 |
| 461 |
Protagonist Therapeutics, Inc
PTGX
NASDAQ
|
Pharmaceutical Preparations | ($130.15M) | FY2025 |
| 462 |
TScan Therapeutics, Inc.
TCRX
NASDAQ
|
Biological Products, (No Diagn... | ($129.77M) | FY2025 |
| 463 |
Oric Pharmaceuticals, Inc.
ORIC
NASDAQ
|
Pharmaceutical Preparations | ($129.47M) | FY2025 |
| 464 |
VARONIS SYSTEMS INC
VRNS
NASDAQ
|
Services-Prepackaged Software | ($129.32M) | FY2025 |
| 465 |
O-I Glass, Inc. /DE/
OI
NYSE
|
Glass Containers | ($129.00M) | FY2025 |
| 466 |
EASTMAN KODAK CO
KODK
NYSE
|
Photographic Equipment & Suppl... | ($128.00M) | FY2025 |
| 467 |
Jade Biosciences, Inc.
JBIO
NASDAQ
|
Pharmaceutical Preparations | ($127.41M) | FY2025 |
| 468 |
Cibus, Inc.
CBUS
NASDAQ
|
Agricultural Chemicals | ($127.09M) | FY2025 |
| 469 |
DuPont de Nemours, Inc.
DD
NYSE
|
Plastic Materials, Synth Resin... | ($126.00M) | FY2025 |
| 470 |
Erasca, Inc.
ERAS
NASDAQ
|
Pharmaceutical Preparations | ($124.55M) | FY2025 |
| 471 |
Midland States Bancorp, Inc.
MSBIP
NASDAQ
|
State Commercial Banks | ($124.28M) | FY2025 |
| 472 |
STEM, INC.
STEM
NYSE
|
Services-Computer Integrated S... | ($124.05M) | FY2022 |
| 473 |
Tonix Pharmaceuticals Holding Corp.
TNXP
NASDAQ
|
Pharmaceutical Preparations | ($124.02M) | FY2025 |
| 474 |
SANGAMO THERAPEUTICS, INC
SGMO
NASDAQ
|
Biological Products, (No Diagn... | ($122.93M) | FY2025 |
| 475 |
Fastly, Inc.
FSLY
NASDAQ
|
Services-Prepackaged Software | ($121.68M) | FY2025 |
| 476 |
Acumen Pharmaceuticals, Inc.
ABOS
NASDAQ
|
Biological Products, (No Diagn... | ($121.34M) | FY2025 |
| 477 |
Green Plains Inc.
GPRE
NASDAQ
|
Industrial Organic Chemicals | ($121.28M) | FY2025 |
| 478 |
Tyra Biosciences, Inc.
TYRA
NASDAQ
|
Pharmaceutical Preparations | ($119.95M) | FY2025 |
| 479 |
Voyager Therapeutics, Inc.
VYGR
NASDAQ
|
Biological Products, (No Diagn... | ($119.72M) | FY2025 |
| 480 |
AlTi Global, Inc.
ALTI
NASDAQ
|
Investment Advice | ($119.70M) | FY2025 |
| 481 |
FORRESTER RESEARCH, INC.
FORR
NASDAQ
|
Services-Engineering, Accounti... | ($119.36M) | FY2025 |
| 482 |
PELOTON INTERACTIVE, INC.
PTON
NASDAQ
|
Sporting & Athletic Goods, NEC | ($118.90M) | FY2025 |
| 483 |
Savara Inc
SVRA
NASDAQ
|
Pharmaceutical Preparations | ($118.84M) | FY2025 |
| 484 |
UNITED NATURAL FOODS INC
UNFI
NYSE
|
Wholesale-Groceries, General L... | ($118.00M) | FY2025 |
| 485 |
enGene Holdings Inc.
ENGNW
NASDAQ
|
Biological Products, (No Diagn... | ($117.30M) | FY2025 |
| 486 |
Korro Bio, Inc.
KRRO
NASDAQ
|
Pharmaceutical Preparations | ($117.26M) | FY2025 |
| 487 |
Solid Biosciences Inc.
SLDB
NASDAQ
|
Biological Products, (No Diagn... | ($117.22M) | FY2019 |
| 488 |
Adicet Bio, Inc.
ACET
NASDAQ
|
Pharmaceutical Preparations | ($116.80M) | FY2025 |
| 489 |
Heartflow, Inc.
HTFL
NASDAQ
|
Surgical & Medical Instruments... | ($116.79M) | FY2025 |
| 490 |
Seaport Entertainment Group Inc.
SEG
NYSE
|
Services-Miscellaneous Amuseme... | ($116.74M) | FY2025 |
| 491 |
Absci Corp
ABSI
NASDAQ
|
Services-Commercial Physical &... | ($115.18M) | FY2025 |
| 492 |
Traeger, Inc.
COOK
NYSE
|
Household Appliances | ($115.18M) | FY2025 |
| 493 |
QUANTUM CORP /DE/
QMCO
NASDAQ
|
Computer Storage Devices | ($115.09M) | FY2025 |
| 494 |
HONEYWELL INTERNATIONAL INC
HON
NASDAQ
|
Aircraft Engines & Engine Part... | ($115.00M) | FY2025 |
| 495 |
OneWater Marine Inc.
ONEW
NASDAQ
|
Retail-Auto & Home Supply Stor... | ($114.58M) | FY2025 |
| 496 |
AMERICOLD REALTY TRUST
COLD
NYSE
|
Real Estate Investment Trusts | ($114.55M) | FY2025 |
| 497 |
MeiraGTx Holdings plc
MGTX
NASDAQ
|
Biological Products, (No Diagn... | ($114.20M) | FY2025 |
| 498 |
FS KKR Capital Corp
FSK
NYSE
|
($114.00M) | FY2025 | |
| 499 |
KESTRA MEDICAL TECHNOLOGIES, LTD.
KMTS
NASDAQ
|
Surgical & Medical Instruments... | ($113.81M) | FY2025 |
| 500 |
IDEAYA Biosciences, Inc.
IDYA
NASDAQ
|
Pharmaceutical Preparations | ($113.70M) | FY2025 |