Top Public Companies by Net Loss
Public companies with the largest reported net losses from their most recent 10-K filing.
Rankings are based on the most recent full fiscal year (FY) value reported in each company's 10-K annual filing with the SEC. Only companies with XBRL-tagged financial data are included. All figures are as reported — negative values indicate a loss. Use the metric tabs to compare across revenue, net income, assets, and more.
Revenue
Net Income
Net Loss
Total Assets
Cash & Equivalents
Long-Term Debt
Profit Margin
Return on Assets
| # | Company | Industry | Net Loss | FY |
|---|---|---|---|---|
| 301 |
Twenty One Capital, Inc.
XXI
NYSE
|
Finance Services | ($217.34M) | FY2025 |
| 302 |
Rigetti Computing, Inc.
RGTIW
NASDAQ
|
Services-Computer Programming... | ($216.21M) | FY2025 |
| 303 |
Immunome Inc.
IMNM
NASDAQ
|
Pharmaceutical Preparations | ($212.39M) | FY2025 |
| 304 |
Disc Medicine, Inc.
IRON
NASDAQ
|
Pharmaceutical Preparations | ($212.18M) | FY2025 |
| 305 |
STARZ ENTERTAINMENT CORP /CN/
STRZ
NASDAQ
|
Services-Motion Picture & Vide... | ($211.20M) | FY2025 |
| 306 |
Damora Therapeutics, Inc.
DMRA
NASDAQ
|
Pharmaceutical Preparations | ($209.84M) | FY2025 |
| 307 |
Verastem, Inc.
VSTM
NASDAQ
|
Pharmaceutical Preparations | ($209.47M) | FY2025 |
| 308 |
Natera, Inc.
NTRA
NASDAQ
|
Services-Medical Laboratories | ($208.16M) | FY2025 |
| 309 |
EXACT SCIENCES CORP
EXAS
NASDAQ
|
Services-Medical Laboratories | ($207.95M) | FY2025 |
| 310 |
Blaize Holdings, Inc.
BZAIW
NASDAQ
|
Semiconductors & Related Devic... | ($206.90M) | FY2025 |
| 311 |
Annexon, Inc.
ANNX
NASDAQ
|
Pharmaceutical Preparations | ($206.69M) | FY2025 |
| 312 |
Bitwise Solana Staking ETF
BSOL
NYSE
|
Commodity Contracts Brokers &... | ($206.54M) | FY2025 |
| 313 |
Playtika Holding Corp.
PLTK
NASDAQ
|
Services-Computer Processing &... | ($206.40M) | FY2025 |
| 314 |
Perimeter Solutions, Inc.
PRM
NYSE
|
Chemicals & Allied Products | ($206.37M) | FY2025 |
| 315 |
Nuvation Bio Inc.
NUVB
NYSE
|
Pharmaceutical Preparations | ($204.63M) | FY2025 |
| 316 |
Wave Life Sciences Ltd.
WVE
NASDAQ
|
Pharmaceutical Preparations | ($204.38M) | FY2025 |
| 317 |
NewAmsterdam Pharma Co N.V.
NAMSW
NASDAQ
|
Pharmaceutical Preparations | ($203.82M) | FY2025 |
| 318 |
Service Properties Trust
SVC
NASDAQ
|
Real Estate Investment Trusts | ($202.32M) | FY2025 |
| 319 |
Under Armour, Inc.
UA
NYSE
|
Apparel & Other Finishd Prods... | ($201.27M) | FY2025 |
| 320 |
Prime Medicine, Inc.
PRME
NASDAQ
|
Biological Products, (No Diagn... | ($201.14M) | FY2025 |
| 321 |
CLARIVATE PLC
CLVT
NYSE
|
Services-Computer Processing &... | ($201.10M) | FY2025 |
| 322 |
Maiden Holdings, Ltd.
MHNC
NYSE
|
Fire, Marine & Casualty Insura... | ($200.97M) | FY2024 |
| 323 |
CUMULUS MEDIA INC
CMLSQ
OTC
|
Radio Broadcasting Stations | ($200.70M) | FY2025 |
| 324 |
Teladoc Health, Inc.
TDOC
NYSE
|
Services-Offices & Clinics of... | ($200.32M) | FY2025 |
| 325 |
1 800 FLOWERS COM INC
FLWS
NASDAQ
|
Retail-Retail Stores, NEC | ($199.99M) | FY2025 |
| 326 |
uniQure N.V.
QURE
NASDAQ
|
Pharmaceutical Preparations | ($198.97M) | FY2025 |
| 327 |
i-80 Gold Corp.
IAUX-WT
NYSE
|
Gold and Silver Ores | ($198.85M) | FY2025 |
| 328 |
Rocket Lab Corp
RKLB
NASDAQ
|
Guided Missiles & Space Vehicl... | ($198.21M) | FY2025 |
| 329 |
Centessa Pharmaceuticals plc
CNTA
NASDAQ
|
Pharmaceutical Preparations | ($197.53M) | FY2025 |
| 330 |
MACERICH CO
MAC
NYSE
|
Real Estate Investment Trusts | ($197.15M) | FY2025 |
| 331 |
BEASLEY BROADCAST GROUP INC
BBGI
NASDAQ
|
Radio Broadcasting Stations | ($196.55M) | FY2025 |
| 332 |
RHYTHM PHARMACEUTICALS, INC.
RYTM
NASDAQ
|
Pharmaceutical Preparations | ($196.54M) | FY2025 |
| 333 |
Karyopharm Therapeutics Inc.
KPTI
NASDAQ
|
Pharmaceutical Preparations | ($196.04M) | FY2025 |
| 334 |
VanEck Bitcoin ETF
HODL
CBOE
|
Commodity Contracts Brokers &... | ($194.00M) | FY2025 |
| 335 |
REGENXBIO Inc.
RGNX
NASDAQ
|
Biological Products, (No Diagn... | ($193.88M) | FY2025 |
| 336 |
GRAN TIERRA ENERGY INC.
GTE
NYSE
|
Crude Petroleum & Natural Gas | ($193.12M) | FY2025 |
| 337 |
TTEC Holdings, Inc.
TTEC
NASDAQ
|
Services-Help Supply Services | ($192.47M) | FY2025 |
| 338 |
RESOURCES CONNECTION, INC.
RGP
NASDAQ
|
Services-Business Services, NE... | ($191.78M) | FY2025 |
| 339 |
SUTRO BIOPHARMA, INC.
STRO
NASDAQ
|
Biological Products, (No Diagn... | ($191.09M) | FY2025 |
| 340 |
Allogene Therapeutics, Inc.
ALLO
NASDAQ
|
Biological Products, (No Diagn... | ($190.89M) | FY2025 |
| 341 |
Fat Brands, Inc
FATPQ
OTC
|
Retail-Eating Places | ($189.85M) | FY2024 |
| 342 |
V F CORP
VFC
NYSE
|
Men's & Boys' Furnishgs, Work... | ($189.72M) | FY2025 |
| 343 |
NEXTNAV INC.
NXNVW
OTC
|
Search, Detection, Navigation,... | ($189.25M) | FY2025 |
| 344 |
Asana, Inc.
ASAN
NYSE
|
Services-Prepackaged Software | ($189.02M) | FY2026 |
| 345 |
FUELCELL ENERGY INC
FCELB
OTC
|
Electrical Industrial Apparatu... | ($187.90M) | FY2025 |
| 346 |
GLAUKOS Corp
GKOS
NYSE
|
Surgical & Medical Instruments... | ($187.69M) | FY2025 |
| 347 |
GD Culture Group Ltd
GDC
NASDAQ
|
Wholesale-Metals & Minerals (N... | ($186.88M) | FY2025 |
| 348 |
Definium Therapeutics, Inc.
DFTX
NASDAQ
|
Medicinal Chemicals & Botanica... | ($183.79M) | FY2025 |
| 349 |
KalVista Pharmaceuticals, Inc.
KALV
NASDAQ
|
Pharmaceutical Preparations | ($183.44M) | FY2025 |
| 350 |
Axsome Therapeutics, Inc.
AXSM
NASDAQ
|
Pharmaceutical Preparations | ($183.17M) | FY2025 |
| 351 |
PureCycle Technologies, Inc.
PCTTW
NASDAQ
|
Plastic Materials, Synth Resin... | ($182.57M) | FY2025 |
| 352 |
DocGo Inc.
DCGO
NASDAQ
|
Services-Health Services | ($182.40M) | FY2025 |
| 353 |
COGENT COMMUNICATIONS HOLDINGS, INC.
CCOI
NASDAQ
|
Communications Services, NEC | ($182.17M) | FY2025 |
| 354 |
Ultra Clean Holdings, Inc.
UCTT
NASDAQ
|
Semiconductors & Related Devic... | ($181.20M) | FY2025 |
| 355 |
ASHFORD HOSPITALITY TRUST INC
AHT-PG
NYSE
|
Real Estate Investment Trusts | ($179.84M) | FY2025 |
| 356 |
StepStone Group Inc.
STEP
NASDAQ
|
Investment Advice | ($179.56M) | FY2025 |
| 357 |
BRANDYWINE REALTY TRUST
BDN
NYSE
|
Real Estate Investment Trusts | ($178.25M) | FY2025 |
| 358 |
Lunai Bioworks Inc.
LNAI
NASDAQ
|
Pharmaceutical Preparations | ($178.01M) | FY2025 |
| 359 |
Health Catalyst, Inc.
HCAT
NASDAQ
|
Services-Computer Programming,... | ($177.97M) | FY2025 |
| 360 |
Celcuity Inc.
CELC
NASDAQ
|
Services-Medical Laboratories | ($177.04M) | FY2025 |
| 361 |
FLAGSTAR BANK, NATIONAL ASSOCIATION
FLG-PU
NYSE
|
Savings Institutions, Not Fede... | ($177.00M) | FY2025 |
| 362 |
MBIA INC
MBI
NYSE
|
Surety Insurance | ($177.00M) | FY2025 |
| 363 |
Zai Lab Ltd
ZLAB
NASDAQ
|
Pharmaceutical Preparations | ($175.54M) | FY2025 |
| 364 |
Triller Group Inc.
ILLRW
OTC
|
Investment Advice | ($174.54M) | FY2025 |
| 365 |
Armata Pharmaceuticals, Inc.
ARMP
NYSE
|
Biological Products, (No Diagn... | ($173.80M) | FY2025 |
| 366 |
FuboTV Inc.
FUBO
NYSE
|
Services-Motion Picture & Vide... | ($172.25M) | FY2024 |
| 367 |
Roivant Sciences Ltd.
ROIV
NASDAQ
|
Pharmaceutical Preparations | ($171.98M) | FY2024 |
| 368 |
ARS Pharmaceuticals, Inc.
SPRY
NASDAQ
|
Pharmaceutical Preparations | ($171.30M) | FY2025 |
| 369 |
Angel Studios, Inc.
ANGX
NYSE
|
Services-Motion Picture & Vide... | ($170.48M) | FY2025 |
| 370 |
Gossamer Bio, Inc.
GOSS
NASDAQ
|
Pharmaceutical Preparations | ($170.37M) | FY2025 |
| 371 |
Cabaletta Bio, Inc.
CABA
NASDAQ
|
Biological Products, (No Diagn... | ($167.86M) | FY2025 |
| 372 |
Edgewise Therapeutics, Inc.
EWTX
NASDAQ
|
Pharmaceutical Preparations | ($167.80M) | FY2025 |
| 373 |
ENVIRI Corp
NVRI
NYSE
|
Services-Services, NEC | ($167.60M) | FY2025 |
| 374 |
Ingevity Corp
NGVT
NYSE
|
Chemicals & Allied Products | ($167.10M) | FY2025 |
| 375 |
Forward Industries, Inc.
FWDI
NASDAQ
|
Finance Services | ($166.97M) | FY2025 |
| 376 |
ArriVent BioPharma, Inc.
AVBP
NASDAQ
|
Pharmaceutical Preparations | ($166.31M) | FY2025 |
| 377 |
Better Home & Finance Holding Co
BETRW
NASDAQ
|
Loan Brokers | ($165.87M) | FY2025 |
| 378 |
Bitwise 10 Crypto Index ETF
BITW
NYSE
|
Commodity Contracts Brokers &... | ($165.86M) | FY2025 |
| 379 |
Larimar Therapeutics, Inc.
LRMR
NASDAQ
|
Pharmaceutical Preparations | ($165.67M) | FY2025 |
| 380 |
Lemonade, Inc.
LMND
NYSE
|
Fire, Marine & Casualty Insura... | ($165.50M) | FY2025 |
| 381 |
NEKTAR THERAPEUTICS
NKTR
NASDAQ
|
Pharmaceutical Preparations | ($164.08M) | FY2025 |
| 382 |
Helmerich & Payne, Inc.
HP
NYSE
|
Drilling Oil & Gas Wells | ($163.70M) | FY2025 |
| 383 |
CrowdStrike Holdings, Inc.
CRWD
NASDAQ
|
Services-Prepackaged Software | ($162.50M) | FY2026 |
| 384 |
Olema Pharmaceuticals, Inc.
OLMA
NASDAQ
|
Pharmaceutical Preparations | ($162.45M) | FY2025 |
| 385 |
Dianthus Therapeutics, Inc. /DE/
DNTH
NASDAQ
|
Pharmaceutical Preparations | ($162.34M) | FY2025 |
| 386 |
Kyverna Therapeutics, Inc.
KYTX
NASDAQ
|
Biological Products, (No Diagn... | ($161.31M) | FY2025 |
| 387 |
MapLight Therapeutics, Inc.
MPLT
NASDAQ
|
Pharmaceutical Preparations | ($161.15M) | FY2025 |
| 388 |
CG Oncology, Inc.
CGON
NASDAQ
|
Biological Products, (No Diagn... | ($161.00M) | FY2025 |
| 389 |
Semnur Pharmaceuticals, Inc.
SMNRW
OTC
|
Pharmaceutical Preparations | ($160.42M) | FY2025 |
| 390 |
Editas Medicine, Inc.
EDIT
NASDAQ
|
Biological Products, (No Diagn... | ($160.06M) | FY2025 |
| 391 |
ServiceTitan, Inc.
TTAN
NASDAQ
|
Services-Prepackaged Software | ($159.85M) | FY2026 |
| 392 |
ASP Isotopes Inc.
ASPI
NASDAQ
|
Miscellaneous Chemical Product... | ($159.84M) | FY2025 |
| 393 |
Magnera Corp
MAGN
NYSE
|
Paper Mills | ($159.00M) | FY2025 |
| 394 |
PBF Energy Inc.
PBF
NYSE
|
Petroleum Refining | ($158.50M) | FY2025 |
| 395 |
Atea Pharmaceuticals, Inc.
AVIR
NASDAQ
|
Pharmaceutical Preparations | ($158.35M) | FY2025 |
| 396 |
Gloo Holdings, Inc.
GLOO
NASDAQ
|
Services-Computer Processing &... | ($157.13M) | FY2025 |
| 397 |
Grayscale Ethereum Classic Trust (ETC)
ETCG
OTC
|
Commodity Contracts Brokers &... | ($157.05M) | FY2025 |
| 398 |
Enovix Corp
ENVX
NASDAQ
|
Miscellaneous Electrical Machi... | ($156.74M) | FY2025 |
| 399 |
COMTECH TELECOMMUNICATIONS CORP /DE/
CMTL
NASDAQ
|
Radio & Tv Broadcasting & Comm... | ($155.30M) | FY2025 |
| 400 |
Spyre Therapeutics, Inc.
SYRE
NASDAQ
|
Pharmaceutical Preparations | ($155.20M) | FY2025 |