Denali Therapeutics Inc. — Insider Transactions
Form 4 filings by directors, officers, and 10%+ shareholders
SEC rules require corporate insiders — including directors, executive officers, and any shareholder owning more than 10% of a company's shares — to report changes in their ownership within two business days of a transaction. These disclosures are filed as Form 4. Open-market purchases (code P) are generally considered the most meaningful signal, as insiders are spending their own money.
| Insider | Title | Type | Shares | Price | Value | Owns After | Date |
|---|---|---|---|---|---|---|---|
| Van Hauwermeiren Timothy | — | Award / Grant | 10,632 | — | — | 10,632 | Nov 4, 2025 |
| Watts Ryan J. | President and CEO | Gift | 50,000 | — | — | 2,152,604 | Sep 3, 2025 |
| Ho Carole | Chief Medical Officer | Sale | 2,937 | $13.58 | $39,884 | 217,391 | Aug 13, 2025 |
| Schuth Alexander O. | COFO and Secretary | Sale | 2,937 | $13.58 | $39,884 | 242,346 | Aug 12, 2025 |
| Ho Carole | Chief Medical Officer | Option Exercise | 44,655 | $0.68 | $30,365 | 220,328 | Aug 5, 2025 |
| Watts Ryan J. | President and CEO | Option Exercise | 455,282 | $0.68 | $309,592 | 708,353 | Jul 9, 2025 |
| BAKER BROS. ADVISORS LP | — | Award / Grant | 10,565 | — | — | 3,415,958 | Jun 3, 2025 |
| Cook Jennifer E. | — | Award / Grant | 6,037 | — | — | 26,075 | Jun 3, 2025 |
| FLATLEY JAY T | — | Award / Grant | 6,037 | — | — | 16,220 | Jun 3, 2025 |
| Klein Peter S | — | Award / Grant | 6,037 | — | — | 27,533 | Jun 3, 2025 |
| Krognes Steve E. | — | Award / Grant | 6,037 | — | — | 31,794 | Jun 3, 2025 |
| Schenkein David P | — | Award / Grant | 6,037 | — | — | 15,257 | Jun 3, 2025 |
| Thornberry Nancy | — | Award / Grant | 6,037 | — | — | 24,717 | Jun 3, 2025 |
| Tessier-Lavigne Marc | — | Award / Grant | 6,037 | — | — | 1,886,576 | Jun 3, 2025 |
| Krognes Steve E. | — | Sale | 3,339 | $20.81 | $69,485 | 25,757 | Jan 7, 2025 |
| Ho Carole | Chief Medical Officer | Sale | 2,907 | $20.81 | $60,495 | 175,673 | Jan 6, 2025 |
| Schuth Alexander O. | COFO and Secretary | Sale | 2,907 | $20.81 | $60,495 | 244,308 | Jan 6, 2025 |
| Watts Ryan J. | President and CEO | Sale | 7,650 | $20.81 | $159,197 | 253,071 | Jan 6, 2025 |
| Watts Ryan J. | President and CEO | Award / Grant | 54,180 | — | — | 289,987 | Jan 3, 2025 |
| Schuth Alexander O. | COFO and Secretary | Award / Grant | 54,180 | — | — | 259,470 | Jan 3, 2025 |
| Ho Carole | Chief Medical Officer | Award / Grant | 54,180 | — | — | 190,835 | Jan 3, 2025 |
| SATO VICKI L | — | Sale | 3,080 | $20.91 | $64,403 | 107,976 | Jan 2, 2025 |
| Krognes Steve E. | — | Sale | 30,000 | $20.25 | $607,500 | 29,096 | Dec 31, 2024 |
| Schuth Alexander O. | COFO and Secretary | Option Exercise | 6,708 | $5.28 | $35,418 | 205,290 | Dec 27, 2024 |
| Ho Carole | Chief Medical Officer | Option Exercise | 17,845 | $0.68 | $12,135 | 136,655 | Nov 25, 2024 |
| Schuth Alexander O. | COFO and Secretary | Option Exercise | 20,516 | $0.68 | $13,951 | 198,582 | Nov 22, 2024 |
| Schenkein David P | — | Sale | 32,312 | $32.87 | $1,062,095 | 9,220 | Nov 11, 2024 |
| Schuth Alexander O. | COFO and Secretary | Option Exercise | 15,558 | $5.28 | $82,146 | 193,624 | Nov 7, 2024 |
| SATO VICKI L | — | Sale | 1,020 | $30.00 | $30,600 | 111,056 | Nov 7, 2024 |
| SATO VICKI L | — | Sale | 3,080 | $27.07 | $83,376 | 112,076 | Nov 1, 2024 |
| Watts Ryan J. | President and CEO | Sale | 40,000 | $27.69 | $1,107,600 | 235,807 | Oct 18, 2024 |
| Krognes Steve E. | — | Sale | 30,000 | $29.03 | $870,900 | 29,096 | Sep 30, 2024 |
| SATO VICKI L | — | Sale | 1,020 | $30.00 | $30,600 | 115,156 | Sep 13, 2024 |
| SATO VICKI L | — | Sale | 100 | $25.37 | $2,537 | 116,176 | Sep 3, 2024 |
| Watts Ryan J. | President and CEO | Sale | 2,260 | $23.79 | $53,765 | 235,807 | Aug 20, 2024 |
| Krognes Steve E. | — | Sale | 1,727 | $23.79 | $41,085 | 32,677 | Aug 20, 2024 |
| Schuth Alexander O. | COFO and Secretary | Sale | 2,453 | $23.79 | $58,357 | 183,966 | Aug 20, 2024 |
| Ho Carole | Chief Medical Officer | Sale | 5,907 | $24.96 | $147,439 | 118,810 | Aug 20, 2024 |
| Schuth Alexander O. | COFO and Secretary | Sale | 2,272 | $22.89 | $52,006 | 186,419 | Aug 13, 2024 |
| Ho Carole | Chief Medical Officer | Sale | 2,337 | $22.89 | $53,494 | 141,268 | Aug 13, 2024 |
| SATO VICKI L | — | Sale | 2,980 | $22.12 | $65,918 | 119,356 | Jul 1, 2024 |
| Krognes Steve E. | — | Sale | 29,900 | $22.12 | $661,388 | 34,504 | Jun 13, 2024 |
| Cook Jennifer E. | — | Sale | 1,458 | $21.73 | $31,682 | 20,038 | Jun 6, 2024 |
| Krognes Steve E. | — | Award / Grant | 5,967 | — | — | 53,308 | May 31, 2024 |
| Thornberry Nancy | — | Award / Grant | 5,967 | — | — | 18,680 | May 31, 2024 |
| Tessier-Lavigne Marc | — | Award / Grant | 5,967 | — | — | 1,880,539 | May 31, 2024 |
| SATO VICKI L | — | Award / Grant | 5,967 | — | — | 122,336 | May 31, 2024 |
| Cook Jennifer E. | — | Award / Grant | 5,967 | — | — | 21,496 | May 31, 2024 |
| Schenkein David P | — | Award / Grant | 5,967 | — | — | 21,496 | May 31, 2024 |
| FLATLEY JAY T | — | Award / Grant | 5,967 | — | — | 10,183 | May 31, 2024 |