Praxis Precision Medicines, Inc. — Insider Transactions
Form 4 filings by directors, officers, and 10%+ shareholders
SEC rules require corporate insiders — including directors, executive officers, and any shareholder owning more than 10% of a company's shares — to report changes in their ownership within two business days of a transaction. These disclosures are filed as Form 4. Open-market purchases (code P) are generally considered the most meaningful signal, as insiders are spending their own money.
| Insider | Title | Type | Shares | Price | Value | Owns After | Date |
|---|---|---|---|---|---|---|---|
| Souza Marcio | Chief Executive Officer | Gift | 400 | — | — | 2,600 | Dec 30, 2025 |
| Nemiroff Alex | General Counsel and Secretary | Option Exercise | 1,714 | $83.85 | $143,719 | 22,546 | Nov 20, 2025 |
| Mastrocola Lauren | Principal Accounting Officer | Option Exercise | 508 | $83.85 | $42,596 | 11,997 | Nov 20, 2025 |
| Kelly Timothy Edwin | Chief Financial Officer | Award / Grant | 384 | $31.62 | $12,142 | 24,663 | Nov 14, 2025 |
| Gross Phillip | — | Sale | 1,661 | $130.10 | $216,096 | 2,080,168 | Oct 16, 2025 |
| MITCHELL DEAN J | — | Option Exercise | 1,932 | $14.36 | $27,744 | 6,932 | Sep 24, 2025 |
| Souza Marcio | Chief Executive Officer | Award / Grant | 348 | $31.54 | $10,976 | 53,907 | May 14, 2025 |
| Kelly Timothy Edwin | Chief Financial Officer | Award / Grant | 249 | $31.54 | $7,853 | 24,279 | May 14, 2025 |
| Nemiroff Alex | General Counsel and Secretary | Tax Withholding | 51 | $85.40 | $4,355 | 20,832 | Feb 12, 2025 |
| Mastrocola Lauren | Principal Accounting Officer | Tax Withholding | 40 | $85.40 | $3,416 | 10,442 | Feb 12, 2025 |
| Souza Marcio | Chief Executive Officer | Tax Withholding | 401 | $85.40 | $34,245 | 53,559 | Feb 12, 2025 |
| Nemiroff Alex | General Counsel and Secretary | Award / Grant | 11,250 | — | — | 21,462 | Jan 12, 2025 |
| Mastrocola Lauren | Principal Accounting Officer | Tax Withholding | 390 | $63.15 | $24,629 | 10,482 | Jan 10, 2025 |
| Souza Marcio | Chief Executive Officer | Award / Grant | 37,500 | — | — | 53,960 | Jan 10, 2025 |
| Kelly Timothy Edwin | Chief Financial Officer | Tax Withholding | 676 | $63.15 | $42,689 | 24,030 | Jan 10, 2025 |
| Souza Marcio | Chief Executive Officer | Tax Withholding | 434 | $77.52 | $33,644 | 16,460 | Jan 7, 2025 |
| Mastrocola Lauren | Principal Accounting Officer | Tax Withholding | 35 | $77.52 | $2,713 | 5,872 | Jan 7, 2025 |
| Nemiroff Alex | General Counsel and Secretary | Tax Withholding | 89 | $77.52 | $6,899 | 10,212 | Jan 7, 2025 |
| Kelly Timothy Edwin | Chief Financial Officer | Tax Withholding | 139 | $77.52 | $10,775 | 12,206 | Jan 7, 2025 |
| Mastrocola Lauren | Principal Accounting Officer | Award / Grant | 294 | $37.40 | $10,996 | 5,907 | Nov 14, 2024 |
| Kelly Timothy Edwin | Chief Financial Officer | Award / Grant | 205 | $37.40 | $7,667 | 12,345 | Nov 14, 2024 |
| Nemiroff Alex | General Counsel and Secretary | Option Exercise | 7,583 | $56.94 | $431,776 | 18,540 | Nov 14, 2024 |
| Mastrocola Lauren | Principal Accounting Officer | Option Exercise | 4,374 | $56.94 | $249,056 | 10,801 | Nov 14, 2024 |
| Nemiroff Alex | General Counsel and Secretary | Award / Grant | 7,800 | — | — | 10,957 | Jul 29, 2024 |
| Mastrocola Lauren | Principal Accounting Officer | Award / Grant | 4,500 | — | — | 6,427 | Jul 29, 2024 |
| Kelly Timothy Edwin | Chief Financial Officer | Award / Grant | 7,800 | — | — | 12,140 | Jul 29, 2024 |
| Kelly Timothy Edwin | Chief Financial Officer | Award / Grant | 606 | $12.37 | $7,496 | 4,340 | May 14, 2024 |
| Souza Marcio | Chief Executive Officer | Award / Grant | 1,718 | $12.37 | $21,252 | 16,894 | May 14, 2024 |
| Mastrocola Lauren | Principal Accounting Officer | Tax Withholding | 48 | $44.65 | $2,143 | 1,927 | Feb 12, 2024 |
| Nemiroff Alex | General Counsel and Secretary | Tax Withholding | 51 | $44.65 | $2,277 | 3,157 | Feb 12, 2024 |
| Souza Marcio | Chief Executive Officer | Tax Withholding | 271 | $44.65 | $12,100 | 15,176 | Feb 12, 2024 |
| Kelly Timothy Edwin | Chief Financial Officer | Tax Withholding | 139 | $25.19 | $3,501 | 3,734 | Jan 7, 2024 |
| Nemiroff Alex | General Counsel and Secretary | Tax Withholding | 89 | $25.19 | $2,242 | 3,208 | Jan 7, 2024 |
| Souza Marcio | Chief Executive Officer | Tax Withholding | 418 | $25.19 | $10,529 | 15,447 | Jan 7, 2024 |
| Mastrocola Lauren | Principal Accounting Officer | Tax Withholding | 35 | $25.19 | $882 | 1,975 | Jan 7, 2024 |
| DeSimone Jill | — | Purchase | 14,500 | $1.75 | $25,375 | 14,500 | Oct 5, 2023 |
| Souza Marcio | Chief Executive Officer | Purchase | 10,000 | $1.06 | $10,600 | 45,002 | Jun 27, 2023 |
| Kelly Timothy Edwin | Chief Financial Officer | Award / Grant | 11,683 | $0.88 | $10,281 | 58,099 | May 12, 2023 |
| Nemiroff Alex | General Counsel and Secretary | Award / Grant | 11,686 | $0.88 | $10,284 | 49,460 | May 12, 2023 |
| Souza Marcio | Chief Executive Officer | Award / Grant | 11,687 | $0.88 | $10,285 | 237,986 | May 12, 2023 |
| MITCHELL DEAN J | — | Purchase | 50,000 | $0.84 | $42,000 | 75,000 | Mar 24, 2023 |
| Kelly Timothy Edwin | Chief Financial Officer | Purchase | 8,000 | $0.87 | $6,960 | 46,416 | Mar 24, 2023 |
| Kelly Timothy Edwin | Chief Financial Officer | Purchase | 8,000 | $0.87 | $6,960 | 46,416 | Mar 24, 2023 |
| Souza Marcio | Chief Executive Officer | Purchase | 35,002 | $0.86 | $30,102 | 35,002 | Mar 23, 2023 |
| Sweeny Nicole | Chief Commercial Officer | Tax Withholding | 1,456 | $3.94 | $5,737 | 38,619 | Feb 12, 2023 |
| Nemiroff Alex | General Counsel and Secretary | Tax Withholding | 920 | $3.94 | $3,625 | 37,774 | Feb 12, 2023 |
| Mastrocola Lauren | Principal Accounting Officer | Tax Withholding | 711 | $3.94 | $2,801 | 30,160 | Feb 12, 2023 |
| Sweeny Nicole | Chief Commercial Officer | Tax Withholding | 2,079 | $2.52 | $5,239 | 40,075 | Jan 7, 2023 |
| Nemiroff Alex | General Counsel and Secretary | Tax Withholding | 1,335 | $2.52 | $3,364 | 38,694 | Jan 7, 2023 |
| Mastrocola Lauren | Principal Accounting Officer | Tax Withholding | 520 | $2.52 | $1,310 | 30,871 | Jan 7, 2023 |