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SPRUCE BIOSCIENCES, INC. — Insider Transactions

Form 4 filings by directors, officers, and 10%+ shareholders

SEC rules require corporate insiders — including directors, executive officers, and any shareholder owning more than 10% of a company's shares — to report changes in their ownership within two business days of a transaction. These disclosures are filed as Form 4. Open-market purchases (code P) are generally considered the most meaningful signal, as insiders are spending their own money.

Overview All Filings Annual Quarterly Insiders
Insider Title Type Shares Price Value Owns After Date
Gharib Samir M. PRESIDENT AND CFO Tax Withholding 184 $80.67 $14,843 8,263 Dec 15, 2025
Szwarcberg Javier B. CHIEF EXECUTIVE OFFICER Option Exercise 1,196 14,922 Dec 15, 2025
Szwarcberg Javier B. CHIEF EXECUTIVE OFFICER Option Exercise 4,950 15,192 Dec 11, 2025
Gharib Samir M. PRESIDENT AND CFO Tax Withholding 680 $88.41 $60,119 7,616 Dec 10, 2025
Gharib Samir M. PRESIDENT AND CFO Tax Withholding 661 $148.16 $97,934 6,066 Oct 20, 2025
Szwarcberg Javier B. CHIEF EXECUTIVE OFFICER Tax Withholding 1,539 $148.16 $228,018 9,474 Oct 20, 2025
Parkman Healthcare Partners LLC Sale 25 $17.46 $437 1,050 Oct 6, 2025
Parkman Healthcare Partners LLC Purchase 256 $17.91 $4,585 1,307 Oct 6, 2025
Charlton Ralph William III CHIEF MEDICAL OFFICER Option Exercise 26,600 150,409 Dec 16, 2024
Gharib Samir M. PRESIDENT AND CFO Tax Withholding 13,291 $0.39 $5,183 350,550 Dec 16, 2024
Szwarcberg Javier B. CHIEF EXECUTIVE OFFICER Option Exercise 89,700 427,801 Dec 10, 2024
Novo Holdings A/S Sale 465,021 $0.75 $348,766 2,550,000 Mar 21, 2024
Novo Holdings A/S Sale 593,000 $0.76 $450,680 3,375,000 Mar 18, 2024
Novo Holdings A/S Sale 1,912,316 $0.89 $1,701,961 4,810,020 Mar 14, 2024
Charlton Ralph William III Chief Medical Officer Award / Grant 9,361 $0.98 $9,174 55,373 Dec 29, 2023
Gharib Samir M. President & CFO Award / Grant 11,255 $0.98 $11,030 202,776 Dec 29, 2023
Charlton Ralph William III Chief Medical Officer Option Exercise 31,750 56,992 Dec 15, 2023
Gharib Samir M. President & CFO Tax Withholding 23,213 $1.66 $38,534 167,153 Dec 15, 2023
Szwarcberg Javier B. Chief Executive Officer Option Exercise 111,000 145,705 Dec 15, 2023
Charlton Ralph William III Chief Medical Officer Award / Grant 12,378 $0.98 $12,130 25,242 Jun 30, 2023
Szwarcberg Javier B. Chief Executive Officer Award / Grant 20,000 $0.98 $19,600 34,705 Jun 30, 2023
Gharib Samir M. President & CFO Award / Grant 10,484 $0.98 $10,274 66,302 Jun 30, 2023
O'Donnell Niall Purchase 630,400 $3.17 $1,998,368 1,326,305 Feb 16, 2023
Novo Holdings A/S Purchase 2,208,000 $3.17 $6,999,360 6,722,336 Feb 16, 2023
Charlton Ralph William III Chief Medical Officer Award / Grant 12,864 $0.93 $11,964 12,864 Dec 30, 2022
Szwarcberg Javier B. Chief Executive Officer Award / Grant 14,705 $0.93 $13,676 14,705 Dec 30, 2022
Gharib Samir M. President & CFO Tax Withholding 15,293 $1.15 $17,587 55,818 Dec 30, 2022
Gharib Samir M. President & CFO Option Exercise 37,500 41,132 Jun 30, 2022
Gharib Samir M. President & CFO Other 2,220 $3.79 $8,414 4,632 Dec 31, 2021
KING RICHARD Chief Executive Officer Other 2,230 $9.53 $21,252 2,230 Jun 30, 2021
Gharib Samir M. Chief Financial Officer Other 1,412 $9.53 $13,456 1,412 Jun 30, 2021
SIMPSON CAMILLA V Option Exercise 334 $0.85 $284 334 May 20, 2021
Novo Holdings A/S Sale 475,000 $13.90 $6,602,500 4,514,336 May 19, 2021
SIMPSON CAMILLA V Sale 14,045 $16.14 $226,686 Apr 30, 2021
Novo Holdings A/S C 4,739,336 4,739,336 Oct 14, 2020
RiverVest Venture Fund III, L.P. C 828,109 1,898,281 Oct 14, 2020
Muralidhar Bali Purchase 200,000 $15.00 $3,000,000 1,792,518 Oct 14, 2020
O'Donnell Niall C 445,905 445,905 Oct 14, 2020
Omega Fund VI GP Manager, Ltd. Purchase 250,000 $15.00 $3,750,000 2,161,022 Oct 14, 2020
Chaya Moghrabi Dina Purchase 250,000 $15.00 $3,750,000 2,161,022 Oct 14, 2020
HealthCap VIII, L.P. C 1,783,621 1,783,621 Oct 14, 2020
HANSSON JONAS Purchase 250,000 $15.00 $3,750,000 2,033,621 Oct 14, 2020