OnKure Therapeutics, Inc. — Insider Transactions
Form 4 filings by directors, officers, and 10%+ shareholders
SEC rules require corporate insiders — including directors, executive officers, and any shareholder owning more than 10% of a company's shares — to report changes in their ownership within two business days of a transaction. These disclosures are filed as Form 4. Open-market purchases (code P) are generally considered the most meaningful signal, as insiders are spending their own money.
| Insider | Title | Type | Shares | Price | Value | Date |
|---|---|---|---|---|---|---|
| Saccomano Nicholas A | President and CEO | Sale | 87 | $2.97 | $258 | Dec 22, 2025 |
| Leverone Jason A. | Chief Financial Officer | Sale | 302 | $2.97 | $897 | Dec 22, 2025 |
| Mathers Edward T | — | Award / Grant | 4,125 | — | — | Sep 30, 2025 |
| Manke Isaac | — | Award / Grant | 5,545 | — | — | Sep 30, 2025 |
| Saccomano Nicholas A | President and CEO | Sale | 88 | $2.62 | $231 | Sep 22, 2025 |
| Leverone Jason A. | Chief Financial Officer | Sale | 303 | $2.62 | $794 | Sep 22, 2025 |
| Mathers Edward T | — | Award / Grant | 4,694 | — | — | Jun 30, 2025 |
| Manke Isaac | — | Award / Grant | 6,311 | — | — | Jun 30, 2025 |
| Saccomano Nicholas A | President and CEO | Sale | 88 | $2.38 | $209 | Jun 23, 2025 |
| Leverone Jason A. | Chief Financial Officer | Sale | 303 | $2.38 | $721 | Jun 23, 2025 |
| Cormorant Private Healthcare Fund III LP | — | Sale | 1,813,439 | $1.85 | $3,354,862 | May 15, 2025 |
| ACORN CAPITAL ADVISORS GP, LLC | — | Purchase | 270,270 | $1.85 | $500,000 | May 15, 2025 |
| Cormorant Global Healthcare Master Fund, LP | — | Sale | 24,300 | $1.99 | $48,357 | May 12, 2025 |
| Saccomano Nicholas A | President and CEO | Sale | 358 | $3.33 | $1,192 | Apr 7, 2025 |
| Leverone Jason A. | Chief Financial Officer | Sale | 1,844 | $2.67 | $4,923 | Apr 4, 2025 |
| Mathers Edward T | — | Award / Grant | 2,580 | — | — | Mar 31, 2025 |
| Manke Isaac | — | Award / Grant | 3,469 | — | — | Mar 31, 2025 |
| Leonard Braden Michael | — | Other | 345,739 | — | — | Oct 7, 2024 |
| Saccomano Nicholas A | President and CEO | Award / Grant | 4,556 | — | — | Oct 4, 2024 |
| Leverone Jason A. | Chief Financial Officer | Award / Grant | 16,331 | — | — | Oct 4, 2024 |
| Carruthers R Michael | — | Award / Grant | 874 | — | — | Oct 4, 2024 |
| Leonard Braden Michael | — | Purchase | 68,746 | $1.50 | $103,119 | Sep 24, 2024 |
| Leonard Braden Michael | — | Purchase | 806 | $1.40 | $1,128 | Sep 17, 2024 |
| Leonard Braden Michael | — | Purchase | 36,176 | $1.40 | $50,646 | Sep 16, 2024 |
| Leonard Braden Michael | — | Purchase | 100,487 | $1.41 | $141,687 | Aug 13, 2024 |
| Leonard Braden Michael | — | Purchase | 335,000 | $1.54 | $515,900 | May 14, 2024 |
| Hall Ashley | Chief Development Officer | Option Exercise | 15,625 | $1.80 | $28,125 | Aug 28, 2023 |
| GREY MICHAEL G | Executive Chairman | Gift | 50,000 | — | — | Jul 26, 2023 |
| Novo Holdings A/S | — | Sale | 100,000 | $7.10 | $710,000 | Jun 23, 2023 |
| O'Donnell Niall | — | Purchase | 125,000 | $8.00 | $1,000,000 | May 8, 2023 |
| Cruse Michael | Chief Operating Officer | Purchase | 7,500 | $3.39 | $25,425 | Sep 1, 2022 |
| GREY MICHAEL G | Executive Chairman | Option Exercise | 50,000 | $1.97 | $98,500 | Aug 31, 2022 |
| Cruse Michael | Chief Operating Officer | Purchase | 3,212 | $3.21 | $10,311 | Aug 29, 2022 |
| Dorenbaum Alejandro | Chief Medical Officer | Gift | 22,348 | — | — | Aug 12, 2022 |
| Jindal Vineet R. | Chief Financial Officer | Award / Grant | 30,000 | — | — | Dec 10, 2021 |
| FLESHER GREGORY J. | President and CEO | Award / Grant | 100,000 | — | — | Dec 10, 2021 |
| Dorenbaum Alejandro | Chief Medical Officer | Award / Grant | 30,000 | — | — | Dec 10, 2021 |
| Cruse Michael | Senior VP-Corporate Operations | Award / Grant | 25,000 | — | — | Dec 10, 2021 |
| Hall Ashley | Chief Development Officer | Award / Grant | 30,000 | — | — | Nov 12, 2021 |
| Jindal Vineet R. | Chief Financial Officer | Purchase | 5,000 | $7.44 | $37,200 | Aug 25, 2021 |
| FLESHER GREGORY J. | President and CEO | Purchase | 8,000 | $8.00 | $64,000 | Aug 25, 2021 |
| Cruse Michael | Senior VP-Corporate Operations | Purchase | 2,500 | $7.45 | $18,625 | Aug 25, 2021 |
| Muralidhar Bali | — | Purchase | 111,736 | $8.50 | $949,756 | Jul 14, 2021 |
| Johnson Wendy S. | Chief Development Officer | Sale | 111,736 | $8.50 | $949,756 | Jul 14, 2021 |
| Johnson Wendy S. | Chief Development Officer | Option Exercise | 111,736 | $1.97 | $220,120 | Jul 8, 2021 |
| Muralidhar Bali | — | Purchase | 20,710 | $9.28 | $192,189 | Jun 23, 2021 |
| Muralidhar Bali | — | Purchase | 14,615 | $8.72 | $127,443 | Jun 21, 2021 |
| Muralidhar Bali | — | Purchase | 16,605 | $9.50 | $157,748 | Jun 8, 2021 |
| Muralidhar Bali | — | Purchase | 12,100 | $9.25 | $111,925 | Jun 4, 2021 |
| Muralidhar Bali | — | Purchase | 14 | $9.50 | $133 | May 28, 2021 |