PROTHENA CORP PUBLIC LTD CO — Insider Transactions
Form 4 filings by directors, officers, and 10%+ shareholders
SEC rules require corporate insiders — including directors, executive officers, and any shareholder owning more than 10% of a company's shares — to report changes in their ownership within two business days of a transaction. These disclosures are filed as Form 4. Open-market purchases (code P) are generally considered the most meaningful signal, as insiders are spending their own money.
| Insider | Title | Type | Shares | Price | Value | Owns After | Date |
|---|---|---|---|---|---|---|---|
| Zago Wagner M. | Chief Scientific Officer | Award / Grant | 85,000 | — | — | 85,000 | Jul 28, 2025 |
| Walker Karin L | Chief Accounting Officer | Award / Grant | 25,000 | — | — | 25,000 | Jul 28, 2025 |
| Swanson Chad J. | Chief Development Officer | Award / Grant | 85,000 | — | — | 85,000 | Jul 28, 2025 |
| Smith Brandon S. | Chief Operating Officer | Award / Grant | 130,000 | — | — | 130,000 | Jul 28, 2025 |
| Nguyen Tran | Chief Strategy Officer and CFO | Award / Grant | 95,000 | — | — | 97,205 | Jul 28, 2025 |
| Malecek Michael J | Chief Legal Officer | Award / Grant | 80,000 | — | — | 80,000 | Jul 28, 2025 |
| Kinney Gene G. | President and CEO | Award / Grant | 140,000 | — | — | 152,793 | Jul 28, 2025 |
| EcoR1 Capital, LLC | — | Sale | 1,984,053 | $7.64 | $15,158,165 | 5,304,596 | May 2, 2025 |
| SCULLY WILLIAM P | — | Gift | 13,200 | — | — | 636,993 | Jan 3, 2025 |
| Walker Karin L | Chief Accounting Officer | Option Exercise | 5,000 | $13.53 | $67,650 | 5,000 | Jan 24, 2024 |
| Walker Karin L | Chief Accounting Officer | Sale | 3,322 | $37.45 | $124,409 | — | Dec 20, 2023 |
| Walker Karin L | Chief Accounting Officer | Option Exercise | 5,000 | $13.53 | $67,650 | 5,000 | Nov 30, 2023 |
| Walker Karin L | Chief Accounting Officer | Option Exercise | 5,000 | $13.53 | $67,650 | 5,000 | Oct 25, 2023 |
| Smith Brandon S. | Chief Operating Officer | Sale | 3,556 | $46.62 | $165,781 | 444 | Oct 11, 2023 |
| Karp Carol D. | Chief Regulatory Officer | Option Exercise | 5,000 | $12.15 | $60,750 | 5,000 | Oct 4, 2023 |
| Malecek Michael J | Chief Legal Officer | Sale | 404 | $48.31 | $19,517 | — | Sep 27, 2023 |
| Walker Karin L | Chief Accounting Officer | Sale | 5,000 | $52.36 | $261,800 | — | Sep 19, 2023 |
| Garren Hideki | Chief Medical Officer | Sale | 2,000 | $55.48 | $110,960 | — | Sep 13, 2023 |
| Smith Brandon S. | Chief Operating Officer | Option Exercise | 4,000 | $11.12 | $44,480 | 4,000 | Sep 13, 2023 |
| Karp Carol D. | Chief Regulatory Officer | Sale | 4,994 | $54.76 | $273,471 | 6 | Sep 6, 2023 |
| Malecek Michael J | Chief Legal Officer | Sale | 2,664 | $55.39 | $147,559 | 14 | Aug 30, 2023 |
| Walker Karin L | Chief Accounting Officer | Sale | 5,000 | $57.18 | $285,900 | — | Aug 18, 2023 |
| Garren Hideki | Chief Medical Officer | Sale | 374 | $59.74 | $22,343 | — | Aug 16, 2023 |
| Smith Brandon S. | Chief Operating Officer | Sale | 401 | $59.91 | $24,024 | — | Aug 16, 2023 |
| Zago Wagner M. | Chief Scientific Officer | Sale | 3,771 | $66.98 | $252,582 | 229 | Aug 2, 2023 |
| Karp Carol D. | Chief Regulatory Officer | Sale | 328 | $67.95 | $22,288 | — | Aug 2, 2023 |
| Malecek Michael J | Chief Legal Officer | Sale | 1,903 | $62.69 | $119,299 | 620 | Jul 26, 2023 |
| Walker Karin L | Chief Accounting Officer | Option Exercise | 5,000 | $15.04 | $75,200 | 5,000 | Jul 19, 2023 |
| Garren Hideki | Chief Medical Officer | Sale | 1,908 | $67.48 | $128,752 | 92 | Jul 12, 2023 |
| Smith Brandon S. | Chief Operating Officer | Option Exercise | 4,000 | $11.12 | $44,480 | 4,000 | Jul 12, 2023 |
| Karp Carol D. | Chief Regulatory Officer | Option Exercise | 5,000 | $12.15 | $60,750 | 5,000 | Jul 5, 2023 |
| Zago Wagner M. | Chief Scientific Officer | Option Exercise | 4,000 | $12.15 | $48,600 | 4,000 | Jul 5, 2023 |
| Selkoe Dennis J. | — | Sale | 5,000 | $67.43 | $337,150 | 2,845 | Jul 3, 2023 |
| Malecek Michael J | Chief Legal Officer | Sale | 1,240 | $69.07 | $85,647 | 3,760 | Jun 28, 2023 |
| Walker Karin L | Chief Accounting Officer | Sale | 2,000 | $67.88 | $135,760 | 3,000 | Jun 20, 2023 |
| Garren Hideki | Chief Medical Officer | Sale | 7,331 | $74.00 | $542,494 | — | Jun 16, 2023 |
| Smith Brandon S. | Chief Operating Officer | Sale | 959 | $74.69 | $71,628 | 1,362 | Jun 14, 2023 |
| Garren Hideki | Chief Medical Officer | Option Exercise | 4,669 | $24.90 | $116,258 | 4,669 | Jun 14, 2023 |
| Zago Wagner M. | Chief Scientific Officer | Sale | 294 | $73.14 | $21,503 | — | Jun 7, 2023 |
| Karp Carol D. | Chief Regulatory Officer | Sale | 3,046 | $69.90 | $212,915 | 16,954 | Jun 7, 2023 |
| Malecek Michael J | Chief Legal Officer | Sale | 711 | $65.98 | $46,912 | — | May 31, 2023 |
| Walker Karin L | Chief Accounting Officer | Option Exercise | 5,000 | $15.04 | $75,200 | 5,000 | May 19, 2023 |
| Kinney Gene G. | President and CEO | Sale | 19,864 | $73.60 | $1,461,990 | 27,727 | May 17, 2023 |
| Nguyen Tran | Chief Strategy Officer and CFO | Sale | 9,215 | $75.44 | $695,180 | 3,300 | May 17, 2023 |
| Selkoe Dennis J. | — | Option Exercise | 9,000 | $23.97 | $215,730 | 17,845 | May 3, 2023 |
| Malecek Michael J | Chief Legal Officer | Sale | 4,680 | $53.40 | $249,912 | 320 | Apr 26, 2023 |
| Walker Karin L | Chief Accounting Officer | Sale | 2,917 | $52.64 | $153,551 | 2,083 | Apr 19, 2023 |
| Malecek Michael J | Chief Legal Officer | Option Exercise | 5,000 | $10.27 | $51,350 | 5,000 | Mar 29, 2023 |
| Walker Karin L | Chief Accounting Officer | Sale | 1,097 | $48.47 | $53,172 | — | Mar 20, 2023 |
| Walker Karin L | Chief Accounting Officer | Sale | 9,431 | $48.14 | $454,008 | 10,569 | Mar 15, 2023 |