Karyopharm Therapeutics Inc. — Insider Transactions
Form 4 filings by directors, officers, and 10%+ shareholders
SEC rules require corporate insiders — including directors, executive officers, and any shareholder owning more than 10% of a company's shares — to report changes in their ownership within two business days of a transaction. These disclosures are filed as Form 4. Open-market purchases (code P) are generally considered the most meaningful signal, as insiders are spending their own money.
| Insider | Title | Type | Shares | Price | Value | Owns After | Date |
|---|---|---|---|---|---|---|---|
| Abate Kristin | Chief Accounting Officer | Award / Grant | 12,799 | — | — | 22,845 | Oct 15, 2025 |
| Poulton Stuart | EVP, Chief Development Officer | Award / Grant | 39,682 | — | — | 67,392 | Oct 15, 2025 |
| Mano Michael | SVP, General Counsel&Secretary | Award / Grant | 43,650 | — | — | 65,075 | Oct 15, 2025 |
| Paulson Richard A. | President and CEO | Award / Grant | 114,285 | — | — | 198,331 | Oct 15, 2025 |
| Cheng Sohanya Roshan | EVP & Chief Commercial Officer | Award / Grant | 43,650 | — | — | 79,506 | Oct 15, 2025 |
| Macomber Lori | EVP, CFO & Treasurer | Award / Grant | 43,650 | — | — | 54,316 | Oct 15, 2025 |
| Abate Kristin | Chief Accounting Officer | Sale | 362 | $6.30 | $2,281 | 10,046 | Oct 1, 2025 |
| Rangwala Reshma | EVP & Chief Medical Officer | Award / Grant | 945 | — | — | 29,798 | Sep 15, 2025 |
| Paulson Richard A. | President and CEO | Sale | 1,257 | $6.43 | $8,083 | 84,046 | Sep 12, 2025 |
| Mano Michael | SVP, General Counsel&Secretary | Sale | 234 | $6.43 | $1,505 | 21,425 | Sep 12, 2025 |
| Poulton Stuart | EVP, Chief Development Officer | Sale | 401 | $6.43 | $2,578 | 27,710 | Sep 12, 2025 |
| Cheng Sohanya Roshan | EVP & Chief Commercial Officer | Sale | 325 | $6.43 | $2,090 | 35,856 | Sep 12, 2025 |
| Abate Kristin | Chief Accounting Officer | Sale | 23 | $6.43 | $148 | 10,408 | Sep 12, 2025 |
| Abate Kristin | Chief Accounting Officer | Sale | 12 | $6.78 | $81 | 9,463 | Sep 3, 2025 |
| Poulton Stuart | EVP, Chief Development Officer | Sale | 191 | $4.37 | $835 | 27,223 | Jul 29, 2025 |
| Abate Kristin | Chief Accounting Officer | Sale | 238 | $4.00 | $952 | 9,475 | Jul 22, 2025 |
| Paulson Richard A. | President and CEO | Sale | 236 | $7.12 | $1,680 | 82,503 | May 6, 2025 |
| Rangwala Reshma | EVP & Chief Medical Officer | Sale | 419 | $6.17 | $2,585 | 28,853 | Apr 23, 2025 |
| Paulson Richard A. | President and CEO | Sale | 245 | $3.74 | $916 | 82,739 | Apr 4, 2025 |
| Cheng Sohanya Roshan | EVP & Chief Commercial Officer | Sale | 3,445 | $6.29 | $21,669 | 34,314 | Mar 4, 2025 |
| Paulson Richard A. | President and CEO | Sale | 11,694 | $6.29 | $73,555 | 82,984 | Mar 4, 2025 |
| Rangwala Reshma | EVP & Chief Medical Officer | Sale | 3,587 | $6.29 | $22,562 | 29,272 | Mar 4, 2025 |
| Poulton Stuart | EVP, Chief Development Officer | Sale | 3,548 | $6.29 | $22,317 | 27,414 | Mar 4, 2025 |
| Abate Kristin | Chief Accounting Officer | Sale | 571 | $6.29 | $3,592 | 9,713 | Mar 4, 2025 |
| Mano Michael | SVP, General Counsel&Secretary | Sale | 2,793 | $6.29 | $17,568 | 21,047 | Mar 4, 2025 |
| Cheng Sohanya Roshan | EVP & Chief Commercial Officer | Award / Grant | 4,583 | — | — | 37,759 | Feb 28, 2025 |
| Rangwala Reshma | EVP & Chief Medical Officer | Award / Grant | 5,416 | — | — | 28,276 | Feb 28, 2025 |
| Poulton Stuart | EVP, Chief Development Officer | Award / Grant | 4,583 | — | — | 30,962 | Feb 28, 2025 |
| Abate Kristin | Chief Accounting Officer | Award / Grant | 933 | — | — | 10,284 | Feb 28, 2025 |
| Paulson Richard A. | President and CEO | Award / Grant | 20,000 | — | — | 94,678 | Feb 28, 2025 |
| Mano Michael | SVP, General Counsel&Secretary | Award / Grant | 3,333 | — | — | 21,590 | Feb 28, 2025 |
| Poulton Stuart | EVP, Chief Development Officer | Sale | 5,914 | $0.63 | $3,726 | 320,714 | Feb 18, 2025 |
| Paulson Richard A. | President and CEO | Sale | 4,099 | $0.65 | $2,664 | 1,120,158 | Feb 4, 2025 |
| Macomber Lori | EVP, CFO & Treasurer | Award / Grant | 160,000 | — | — | 160,000 | Jan 31, 2025 |
| Paulson Richard A. | President and CEO | Sale | 4,055 | $0.78 | $3,163 | 1,124,257 | Jan 6, 2025 |
| Paulson Richard A. | President and CEO | Sale | 3,620 | $0.81 | $2,932 | 1,128,312 | Dec 4, 2024 |
| Paulson Richard A. | President and CEO | Sale | 3,675 | $0.91 | $3,344 | 1,131,932 | Nov 5, 2024 |
| Paulson Richard A. | President and CEO | Sale | 3,607 | $0.88 | $3,174 | 1,135,607 | Oct 4, 2024 |
| Paulson Richard A. | President and CEO | Sale | 3,667 | $0.72 | $2,640 | 1,139,214 | Sep 4, 2024 |
| Mano Michael | SVP, General Counsel&Secretary | Sale | 3,971 | $0.72 | $2,859 | 273,881 | Sep 4, 2024 |
| Mason Michael | EVP, CFO & Treasurer | Sale | 7,050 | $0.72 | $5,076 | 391,054 | Sep 4, 2024 |
| Cheng Sohanya Roshan | EVP & Chief Commercial Officer | Sale | 5,356 | $0.72 | $3,856 | 404,051 | Sep 4, 2024 |
| Paulson Richard A. | President and CEO | Sale | 3,608 | $0.93 | $3,355 | 1,142,881 | Aug 6, 2024 |
| Poulton Stuart | EVP, Chief Development Officer | Sale | 2,883 | $1.06 | $3,056 | 326,628 | Jul 30, 2024 |
| Paulson Richard A. | President and CEO | Sale | 3,616 | $0.85 | $3,074 | 1,146,489 | Jul 5, 2024 |
| PAKIANATHAN DEEPIKA | — | Sale | 117,307 | $0.98 | $114,961 | 229,308 | Jun 5, 2024 |
| Mason Michael | EVP, CFO & Treasurer | Sale | 652 | $0.99 | $645 | 398,104 | Jun 4, 2024 |
| Paulson Richard A. | President and CEO | Sale | 3,592 | $0.99 | $3,556 | 1,150,105 | Jun 4, 2024 |
| PAKIANATHAN DEEPIKA | — | Sale | 357,256 | $1.00 | $357,256 | 1,147,875 | May 31, 2024 |
| Paulson Richard A. | President and CEO | Sale | 3,576 | $1.13 | $4,041 | 1,153,697 | May 6, 2024 |