Lyra Therapeutics, Inc. — Insider Transactions
Form 4 filings by directors, officers, and 10%+ shareholders
SEC rules require corporate insiders — including directors, executive officers, and any shareholder owning more than 10% of a company's shares — to report changes in their ownership within two business days of a transaction. These disclosures are filed as Form 4. Open-market purchases (code P) are generally considered the most meaningful signal, as insiders are spending their own money.
| Insider | Title | Type | Shares | Price | Value | Owns After | Date |
|---|---|---|---|---|---|---|---|
| PERCEPTIVE ADVISORS LLC | — | Sale | 3,213 | $3.90 | $12,531 | 14,026 | Nov 13, 2025 |
| EDELMAN JOSEPH | — | Sale | 3,247 | $5.18 | $16,819 | 22,521 | Nov 10, 2025 |
| Palasis Maria | President & CEO | Sale | 1,565 | $8.91 | $13,944 | 1,098,435 | Jul 10, 2025 |
| Cavalier Jason | Chief Financial Officer | Sale | 684 | $8.91 | $6,094 | 519,316 | Jul 10, 2025 |
| Palasis Maria | President & CEO | Award / Grant | 800,000 | — | — | 1,100,000 | Jan 8, 2025 |
| Cavalier Jason | Chief Financial Officer | Award / Grant | 420,000 | — | — | 520,000 | Jan 8, 2025 |
| Palasis Maria | President & CEO | Award / Grant | 300,000 | — | — | 300,000 | Oct 16, 2024 |
| Cavalier Jason | Chief Financial Officer | Award / Grant | 100,000 | — | — | 100,000 | Oct 16, 2024 |
| Waksal Harlan | Executive Chair | Award / Grant | 275,000 | — | — | 536,966 | Mar 18, 2024 |
| Waksal Harlan | Executive Chair | Purchase | 25,000 | $2.96 | $74,000 | 261,966 | Nov 10, 2023 |
| North Bridge Venture Partners VI L P | — | Purchase | 197,946 | $2.43 | $481,009 | 1,107,370 | May 31, 2023 |
| ANDERSON EDWARD T | — | Purchase | 197,946 | $2.43 | $481,009 | 1,107,370 | May 31, 2023 |
| Perceptive LS (A), LLC | — | Purchase | 3,610,832 | $2.49 | $8,990,972 | 11,469,117 | May 31, 2023 |
| Richard Robert E. | SVP, Technical Operations | Award / Grant | 30,000 | — | — | 30,000 | Jan 31, 2023 |
| Noyes Corinne | See Remarks | Award / Grant | 36,667 | — | — | 36,667 | Jan 31, 2023 |
| MERRIFIELD C ANN | — | Purchase | 4,000 | $5.05 | $20,200 | 11,328 | Jun 10, 2022 |
| MERRIFIELD C ANN | — | Purchase | 328 | $5.00 | $1,640 | 7,328 | May 13, 2022 |
| PERCEPTIVE ADVISORS LLC | — | Purchase | 5,924,170 | $4.22 | $24,999,997 | 7,858,285 | Apr 12, 2022 |
| NORTH BRIDGE VENTURE PARTNERS V A LP | — | Purchase | 527,806 | $4.22 | $2,227,341 | 909,424 | Apr 12, 2022 |
| ANDERSON EDWARD T | — | Purchase | 527,806 | $4.22 | $2,227,341 | 909,424 | Apr 12, 2022 |
| Waksal Harlan | Executive Chair | Purchase | 236,966 | $4.22 | $999,997 | 236,966 | Apr 12, 2022 |
| MERRIFIELD C ANN | — | Purchase | 3,500 | $8.97 | $31,395 | 3,500 | Jun 17, 2021 |
| snyderman nancy lynn MD | — | Purchase | 1,025 | $9.72 | $9,963 | 1,025 | Dec 16, 2020 |
| PERCEPTIVE LIFE SCIENCES MASTER FUND LTD | — | Purchase | 625,000 | $16.00 | $10,000,000 | 1,934,115 | May 5, 2020 |
| Soleus Capital Master Fund, L.P. | — | X | 31,382 | $8.63 | $270,827 | 474,330 | May 5, 2020 |
| PERCEPTIVE ADVISORS LLC | — | Tax Withholding | 76,172 | $16.00 | $1,218,752 | 1,309,115 | May 5, 2020 |
| DAMORE RICHARD A | — | C | 651,453 | — | — | 651,453 | May 5, 2020 |
| WHITESIDES GEORGE M | — | C | 6,404 | — | — | 55,064 | May 5, 2020 |
| POLARIS VENTURE PARTNERS IV LP | — | C | 316,980 | — | — | 316,980 | May 5, 2020 |
| Roberts Carmichael | — | C | 415 | — | — | 58,414 | May 5, 2020 |
| ANDERSON EDWARD T | — | X | 10,322 | $8.63 | $89,079 | 329,625 | May 5, 2020 |
| LANGER ROBERT | — | C | 668 | — | — | 15,167 | May 5, 2020 |
| MCGUIRE TERRANCE | — | C | 19,370 | — | — | 19,370 | May 5, 2020 |
| WHITESIDES GEORGE M | — | Award / Grant | 19,661 | $16.00 | $314,576 | 48,660 | May 1, 2020 |