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IONIS PHARMACEUTICALS INC — Insider Transactions

Form 4 filings by directors, officers, and 10%+ shareholders

SEC rules require corporate insiders — including directors, executive officers, and any shareholder owning more than 10% of a company's shares — to report changes in their ownership within two business days of a transaction. These disclosures are filed as Form 4. Open-market purchases (code P) are generally considered the most meaningful signal, as insiders are spending their own money.

Overview All Filings Annual Quarterly Insiders
Insider Title Type Shares Price Value Owns After Date
WENDER JOSEPH H Sale 7,429 $81.23 $603,458 36,035 Dec 1, 2025
KLEIN JOSEPH III Option Exercise 4,000 4,000 Nov 25, 2025
Devers Shannon L. EVP, Chief Human Resources Ofc Option Exercise 16,777 $53.77 $902,099 34,271 Nov 25, 2025
HERMAN JOAN E Option Exercise 12,000 $40.05 $480,600 58,086 Nov 19, 2025
WENDER JOSEPH H Option Exercise 16,000 $24.42 $390,720 16,000 Nov 18, 2025
Birchler Brian EVP, Corp and Development Ops Sale 8,000 $76.17 $609,360 48,826 Nov 6, 2025
Geary Richard S EVP, Chief Development Officer Sale 800 $75.01 $60,008 59,657 Nov 5, 2025
Geary Richard S EVP, Chief Development Officer Sale 905 $75.05 $67,920 59,657 Nov 3, 2025
Geary Richard S EVP, Chief Development Officer Option Exercise 34,585 $60.89 $2,105,881 114,242 Nov 3, 2025
WENDER JOSEPH H Sale 5,975 $73.85 $441,254 75,235 Oct 31, 2025
LOSCALZO JOSEPH Option Exercise 16,000 $52.22 $835,520 52,330 Oct 31, 2025
Swayze Eric EVP Research Sale 53 $73.62 $3,902 256 Oct 15, 2025
PARSHALL B LYNNE Sale 5,000 $71.74 $358,700 61,344 Oct 15, 2025
Devers Shannon L. EVP, Chief Human Resources Ofc Sale 1,263 $73.62 $92,982 17,494 Oct 15, 2025
Birchler Brian EVP, Corp and Development Ops Sale 12,425 $72.23 $897,458 56,826 Oct 15, 2025
Swayze Eric EVP Research Sale 6,849 $69.02 $472,718 30,453 Oct 6, 2025
O'NEIL PATRICK R. EVP CLO & General Counsel Sale 3,241 $69.27 $224,504 53,889 Oct 6, 2025
Monia Brett P Chief Executive Officer Sale 437 $69.26 $30,267 179,572 Oct 6, 2025
Baroldi Joseph EVP, Chief Business Officer Sale 1,625 $69.37 $112,726 30,301 Oct 6, 2025
Swayze Eric EVP Research Option Exercise 14,142 $53.77 $760,415 51,444 Oct 2, 2025
O'NEIL PATRICK R. EVP CLO & General Counsel Option Exercise 34,461 $60.89 $2,098,330 91,591 Oct 2, 2025
Baroldi Joseph EVP, Chief Business Officer Option Exercise 15,000 $31.80 $477,000 46,926 Oct 2, 2025
WENDER JOSEPH H Sale 16,800 $65.50 $1,100,400 92,035 Oct 1, 2025
O'NEIL PATRICK R. EVP CLO & General Counsel Sale 10,473 $64.54 $675,927 57,130 Sep 30, 2025
Geary Richard S EVP, Chief Development Officer Option Exercise 57,900 $53.77 $3,113,283 137,557 Sep 30, 2025
HOUGEN ELIZABETH L EVP, Finance & CFO Sale 49,800 $65.26 $3,249,948 110,500 Sep 30, 2025
O'NEIL PATRICK R. EVP CLO & General Counsel Option Exercise 1,700 $56.78 $96,526 58,830 Sep 12, 2025
Baroldi Joseph EVP, Chief Business Officer Sale 11,950 $62.16 $742,812 31,926 Sep 9, 2025
O'NEIL PATRICK R. EVP CLO & General Counsel Sale 1,000 $64.56 $64,560 57,130 Sep 9, 2025
Baroldi Joseph EVP, Chief Business Officer Option Exercise 250 $31.80 $7,950 32,176 Sep 5, 2025
BENNETT C FRANK EVP, Chief Scientific Officer Sale 6,000 $59.60 $357,600 82,679 Sep 5, 2025
Monia Brett P Chief Executive Officer Option Exercise 42,030 $37.58 $1,579,487 308,324 Sep 3, 2025
KLEIN JOSEPH III Sale 28,000 $60.00 $1,680,000 Sep 3, 2025
KLEIN JOSEPH III Sale 28,000 $60.00 $1,680,000 Sep 3, 2025
Devers Shannon L. EVP, Chief Human Resources Ofc Option Exercise 2,234 $37.58 $83,954 18,171 Sep 3, 2025
Baroldi Joseph EVP, Chief Business Officer Option Exercise 2,800 $31.80 $89,040 34,726 Sep 3, 2025
LOSCALZO JOSEPH Option Exercise 16,000 $24.42 $390,720 52,330 Sep 3, 2025
Schneider Eugene EVP, Chf Clinical Develop Ofcr Option Exercise 19,658 $53.77 $1,057,011 71,165 Sep 3, 2025
Swayze Eric EVP Research Sale 10,000 $49.22 $492,200 38,432 Sep 2, 2025
WENDER JOSEPH H Sale 5,600 $57.53 $322,168 120,035 Sep 2, 2025
PARSHALL B LYNNE Sale 10,750 $50.42 $542,015 75,594 Sep 2, 2025
Geary Richard S EVP, Chief Development Officer Sale 10,000 $50.37 $503,700 79,657 Sep 2, 2025
WENDER JOSEPH H Sale 5,600 $57.53 $322,168 120,035 Sep 2, 2025
O'NEIL PATRICK R. EVP CLO & General Counsel Option Exercise 49,800 $53.77 $2,677,746 57,130 Sep 2, 2025
BENNETT C FRANK EVP, Chief Scientific Officer Option Exercise 12,891 $61.50 $792,797 88,679 Sep 2, 2025
O'NEIL PATRICK R. EVP CLO & General Counsel Other 331 $27.71 $9,172 57,130 Aug 29, 2025
Monia Brett P Chief Executive Officer Other 189 $27.71 $5,237 180,009 Aug 29, 2025
Geary Richard S EVP, Chief Development Officer Other 165 $27.71 $4,572 89,657 Aug 29, 2025
BENNETT C FRANK EVP, Chief Scientific Officer Other 213 $27.71 $5,902 93,679 Aug 29, 2025
Birchler Brian EVP, Corp and Development Ops Other 166 $27.71 $4,600 56,826 Aug 29, 2025